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In vivo models
MODELS OF ALS-PDC

CNS’s proprietary animal model for neurodegeneration re-creates in mice and rats, a cluster neurodegeneration (ALS-Parkinsonism Dementia Complex of the Western Pacific; ALS-PDC)...MORE

MODELS OF EPILEPSY
Current models do not accurately mimic many of the features of Temporal Lobe Epilepsy (TLE) in humans. This is because clinical TLE often originates early in development (time of birth or childhood) ...MORE
   
MODELS OF FOCAL STROKE
CNS has proven expertise in the application of two of the most commonly used models of focal stroke: the intraluminal thread model of middle cerebral artery occlusion ...MORE
MODELS OF GLOBAL STROKE
Two of the most commonly used models of global stroke are neonatal hypoxia-ischemia (HI) and carotid vessel occlusion; CNS has expertise in both of these models. ...MORE
   
MODELS OF SCHIZOPHRENIA
There is a serious lack of well-validated animal models of schizophrenia that combine appropriate behavioural and pathological markers of the disease. Schizophrenia is also known to be largely ...MORE
 
Cognitive Function and Behavioral Testing

CNS offers numerous tests to assess learning and memory processes. In addition to the multiplicity of tests, each may be run in various ways, depending on which aspects or learning and/or memory the client is interested in exploring. All work is properly blinded and digitally recorded for arms-length evaluation and is provided as a record with the final report.

Some of the more generally employed methodologies include
(Hover over for complete description)
   
Open Field
Conditioned Place Preference
 
T-Maze and Y-Maze
Spatial Learning and Memory
 
Executive Function
Motor Function
   
The Learning-Performance Distinction
 

 

In developing countries
Alzheimer’s is the 4th leading
contributor of death in the
elderly – behind heart disease,
cancer and strokes.

Over 15 million people
worldwide are believed
to suffer with Alzheimer’s
disease – a number expected
to double by 2030.

 

CNS events ...
BIoPartnering North America, Vancouver, February 27, 28 2012
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